A German PhD usually takes 3-4 years. Traditional programmes focus on independent research, but more structured PhDs involve additional training units (worth 180-240 ECTS credits) as well as placement opportunities. Both options require you to produce a thesis and present it for examination. Many programmes are delivered in English.
Epigenetic research aims to understand heritable gene regulation that is not directly encoded in the DNA sequence. Epigenetic mechanisms such as DNA methylation and histone modifications modulate the packaging of the DNA in the nucleus and thereby influence gene expression.
PhD THESIS Epigenetic mechanisms involved in stem cell differentiation Coordinator: Acad. Maya Simionescu PhD Student: Florin Iordache Bucharest 2013. Table of contents INTRODUCTION PART I. CURRENT STATE OF KNOWLEDGE CHAPTER I.1 Endothelial progenitor cells.6 I.1.1 Definition and characteristics of stem cells.6 I.1.2 Classification and types of stem cells.8 I.1.3 Umbilical cord.Schizophrenia is a chronic disease leading to impairment in social and occupational functioning. The etiology remains elusive. Current concepts presume a genetic susceptibility, which in combination with environmental stimuli leads to the clinical manifestation. Cognitive dysfunction, especially deficits in working memory are regarded core deficits in schizophrenia.Epigenetic studies modifications of DNA or proteins of the chromatin, which do not change the DNA sequence but modify gene expression. There are numerous studies about epigenetic modifications, influencing factors and effects of these modifications in human and murine cells.
The Developing Genome: An Introduction to Behavioral Epigenetics. Authors. David S. Moore, Pitzer College Follow. Files. Description. Why do we grow up to look, act, and feel as we do? Through most of the 20th century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a.
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ZORA (Zurich Open Repository and Archive) provides open and worldwide access to the research and scholarly output of the University of Zurich, Switzerland. A focus is on qualified scientific publications. ZORA is operated by the Main Library together with the Zentrale Informatik of the University of Zurich. Latest Additions. Gastroesophageal reflux. Kook, Peter H (2014). In: Bonagura, John D.
A vast array of successive epigenetic modifications ensures the creation of a healthy individual. Crucial epigenetic reprogramming events occur during germ cell development and early embryogenesis.
DNA methylation is an epigenetic mechanism that occurs by the addition of a methyl (CH 3) group to DNA, thereby often modifying the function of the genes and affecting gene expression. The most widely characterized DNA methylation process is the covalent addition of the methyl group at the 5-carbon of the cytosine ring resulting in 5-methylcytosine (5-mC), also informally known as the “fifth.
Link zu u:search. Abstract in Englisch. Collagen, the main component of bone extracellular matrix (ECM) represents a protein with a defined super-molecular organization. For stabl.
Epigenetic processes include the establishment, maintenance and coordinated change of DNA and histone modifications to shape chromatin structure across cell divisions without affecting the DNA sequence. This thesis addresses the Regulation of DNA methylation with particular focus on the interplay between epigenetic factors DNMT1 and UHRF1, their role during development and disease as well as.
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Futures of Technology, Science and Society. This interdisciplinary series of books is devoted to technology futures in their scientific and societal contexts. The use of the plural “futures” is by no means accidental: firstly, light is to be shed on a broad spectrum of developments in science and technology; secondly, debates on technoscientific fields such as biotechnology, information.
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